My Friend's Little Sister Has It In for Me!

Synopsis

For high schooler Akiteru Oboshi, the whole youthful experience thing—like fun, friendships, and even having a girlfriend—is a complete waste of time. So when his best friend’s sister, Iroha Kohinata, keeps teasing him, Akiteru naturally finds it annoying. She practically lives in his room, she’s always on his bed, she’s just a raging storm of clinginess! Why is she only annoying around him?!

First Air Date: 2025-10-04

Last Air Date: 2025-12-20

Number of Seasons: 1

Number of Episodes: 12

Networks: HTB, tv asahi, Nagoya TV, KBC, ABC TV, NCC, OAB, ABA, Niigata Television Network 21, khb, KFB, HOME, KSB, Kagoshima Broadcasting, Iwate Asahi TV, Akita Asahi Broadcasting, Yamagata Television System, Shizuoka Asahi TV, Asahi Broadcasting Nagano, Hokuriku Asahi Broadcasting, Ehime Asahi TV, Yamaguchi Asahi Broadcasting, Kumamoto Asahi Broadcasting, Ryu-Q Asahi Broadcasting

View Technical Specifications on IMDb

Top Cast

Haruki Ishiya as Akiteru Oboshi (voice)
Sayumi Suzushiro as Iroha Kohinata (voice)
Tomori Kusunoki as Mashiro Tsukinomori (voice)
Soma Saito as Ozuma Kohinata (voice)
Kana Hanazawa as Sumire Kageishi (voice)

Seasons

Season 1 (2025)

No overview available for this season.

Episodes:

Ep. 1: My Friend's Little Sister Has It In for Me (2025-10-04)

Akiteru just wants to work toward his future, but his friend's little sister won't allow him any peace.
Ep. 2: The Cousin I Haven't Seen in Years Is Cold to Me (2025-10-11)

Now that Mashiro has moved to his school, can Akiteru manage to make her open up to him?
Ep. 3: Only I Can Be a Pain to My Uncle’s Daughter (2025-10-18)

Akiteru decides to throw a welcome party for Mashiro, but first he must convince her to attend.
Ep. 4: My Friend's Little Sister Might Be a Delinquent (2025-10-25)

Akiteru and Iroha recall how they first met.
Ep. 5: My Friend's Little Sister Keeps Getting Close to Me (2025-11-01)

A look back at how Iroha came to be the voice actress for 05th Floor Alliance.
Ep. 6: My Friend's Little Sister Has It In for My Friend's Enemy (2025-11-08)

While at the mall with Mashiro and Iroha, Akiteru learns why Mashiro left her old school.
Ep. 7: The Girl Who Confessed to Me Is Cold to Me in Reality (2025-11-15)

Akiteru tries to give a proper reply to Mashiro's love confession, but she's brutally cold to him in person.
Ep. 8: Everyone I Know Is Being Weird With Me (2025-11-22)

Sumire asks Akiteru for help with a problem that could endanger her future with 05th Floor Alliance.
Ep. 9: My Fake Girlfriend Gets Tough When I Respond To Her Confession (2025-11-29)

Akiteru and Iroha head to Otoi's studio to record for the game, but Iroha has ideas of her own.
Ep. 10: My Friend's Little Sister Only Gets an Apology from Me (2025-12-06)

Akiteru must clear the air with Iroha to keep 05th Floor Alliance running smoothly.
Ep. 11: We're Perfect for Training the Drama Club (2025-12-13)

With 05th Floor Alliance's help, the drama club is ready for the big competition... but then disaster strikes.
Ep. 12: My Friend's Little Sister Really Does Have It In for Me (2025-12-20)

Can Akiteru save the drama club and secure 05th Floor Alliance's future?